Wyizolowany kwas nukleinowy, ssaczy wektor ekspresyjny, fuzje polipeptydowe, komórki gospodarza, sposób wytwarzania fuzji polipeptydowych, sposoby in vitro i ex vivo modyfikowania profilu glikozylacji, wyizolowana cząsteczka kwasu nukleinowego

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专利权人:

ROCHE GLYCART AG

发明人:

UMANA PABLO,BRUENKER PETER,FERRARA CLAUDIA,SUTER TOBIAS

申请号：

PL41546304

公开号：

PL224787B1

申请日:

2004.01.22

申请国别(地区):

PL

年份:

2017

代理人:

摘要：

The present invention relates to the field of glycosylation engineering of proteins. More particularly, the present invention relates to nucleic acid molecules, including fusion constructs, having catalytic activity and the use of same in glycosylation engineering of host cells to generate polypeptides with improved therapeutic properties, including antibodies with increased Fc receptor binding and increased effector function.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/