Imidazole compounds for the treatment of neurodegenerative disorders.

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专利权人:

PFIZER PRODUCTS INC

发明人:

BRODNEY MICHAEL AARON,COFFMAN KAREN JEAN

申请号：

AP2006003727

公开号：

AP2379A

申请日:

2005.03.11

申请国别(地区):

AP

年份:

2012

代理人:

摘要：

The present invention relates to compounds of the Formula I wherein R<；SUP>；1<；/SUP>；, R<；SUP>；2<；/SUP>；, R<；SUP>；3<；/SUP>；, R<；SUP>；4<；/SUP>；, R<；SUP>；6<；/SUP>；, R<；SUP>；7 <；/SUP>；and A are as defined. Compounds of the Formula I have activity inhibiting production of Abeta-peptide. The invention also relates to pharmaceutical compositions and methods for treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.

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