Disclosed are systems and methods for aligning an ophthalmic device with respect to an eye of a patient. In one disclosure, the system may include an ophthalmic device with an on-axis and an off-axis. The system may include an on-axis illuminator that emits light that is reflected by the eye of the patient to form an on-axis reflection having a center. The system may include an on-axis camera pointed along the on-axis. The system may include an off-axis illuminator that emits light that is reflected by the eye to form an off-axis reflection having a center. The system may include an off-axis camera pointed along the off-axis. The ophthalmic device may be operable to be aligned with respect to the eye of the patient when the on-axis is substantially normal to the center of the on-axis reflection and the off-axis is substantially normal to the center of the off-axis reflection.