Weinstein, David E.,Jain, Sarita K.,Finck, Barbara
申请号:
AU2018249822
公开号:
AU2018249822A1
申请日:
2018.04.03
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Methods of treatment of progressive supranuclear palsy or its symptoms, with PPARγ agonists, and in particular, the compound of formula (I) known as INT 131: Formula (I). Also provided are methods of treating a subject that include selecting a subject having an elevated level of neurofilament light chain protein in a sample obtained from the subject, as compared to a reference level of neurofilament light chain protein, and administering a pharmaceutical composition including a therapeutically effective amount of a compound of formula (I) to the selected subject.