WOLKENBERG, SCOTT,HARRISON, SCOTT T.,BARROW, JAMES C.,ZHAO, ZHIJIAN,KETT, NATHAN,ZARTMAN, AMY,MELAMED, JEFFREY
申请号：
PL11751129
公开号：
PL2542084T3
申请日:
2011.02.28
申请国别(地区):
PL
年份:
2018
代理人:
摘要：
The present invention relates to 4-pyrimidinone compounds which are inhibitors of catechol O-methyltransferase (COMT), and are useful in the treatment and prevention of neurological and psychiatric disorders and diseases in which COMT enzyme is involved. The present invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which COMT is involved.
