The present invention relates to a novel antibody capable of binding to ADAM17 and also the amino and nucleic acid sequences coding for said antibody. From one aspect, the invention relates to a novel antibody, or antigen-binding fragments, capable of binding to ADAM17 with anti-tumour activities. The invention also comprises the use of said antibody as a drug for the treatment of cancer. Finally, the invention comprises compositions comprising said antibody, alone or in combination or conjugation with other anti-cancer compounds, and the use of same for the treatment of cancer.本發明係有關於能夠結合至ADAM17之新穎的抗體,以及還有編碼該抗體之胺基酸和核酸序列。由一個態樣,本發明係有關於新穎的抗體或抗原結合片段,其能結合至ADAM17且具有抗腫瘤活性。本發明亦包含該抗體作為治療癌症的藥物之用途。最後,本發明包含組成物,其含有該抗體,單獨或組合或是結合其他的抗癌化合物,以及其等用於治療癌症之用途。
