SCHAFFER David V.,KLIMCZAK Ryan R.,KOERBER James T.,FLANNERY John G.,DALKARA MOUROT Deniz,VISEL Meike,BYRNE Leah C.T.,VISEL Me
申请号：
SI201231053
公开号：
SI2699270T1
申请日:
2012.04.20
申请国别(地区):
SI
年份:
2017
代理人:
摘要：
The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells, when administered via intravitreal injection, compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease.
