Chen, Cheng,Kong, Jongrock,Humphrey, Guy,Dolman, Sarah,Li, Hongmei,Tudge, Matthew T.,Yong, Kelvin,Xiang, Bangping,Zacuto, Michael
申请号:
AU2011344075
公开号:
AU2011344075A1
申请日:
2011.12.13
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to macrolactam compounds, intermediates useful in the preparation of macrolactams, methods for preparing the intermediates, and methods for preparing and modifying macrolactams. One use of the compounds and methods described herein is in the production of macrolactam compounds able to inhibit HCV NS3 protease activity. An example of an HCV inhibitory compound that can be synthesized using the procedures described herein is Compound A and derivative thereof.