UNIVESIDAD COMPLUTENSE DE MADRID;UNIVERSITEIT GENT
发明人:
Koen Raemdonck,Stefaan De Smedt,Jésus Pérez-Gil
申请号:
US16463946
公开号:
US20200197496A1
申请日:
2017.11.23
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention in particular relates to the field of micro- and nanoparticles, more in particular to coated nanoparticles. The coatings of the present invention in particular comprise surfactant protein B (SP-B) and one or more lipids. The invention further relates to such coated particles and compositions comprising them for use as a medicament, in particular for use in the treatment of various disorders. Furthermore, the invention provides the use of the compositions of the current invention for delivering one or more agents, such as small interfacing RNA (siRNA) molecules, to the target tissue or cells.