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ANTÍGENO SUSTITUTO EN ENFERMEDADES AUTOINMUNES.
专利权人:
LLC;OPKO PHARMACEUTICALS
发明人:
FROST, Phillip,KODADEK, Thomas
申请号:
MX2013008001
公开号:
MX344791B
申请日:
2012.01.09
申请国别(地区):
MX
年份:
2017
代理人:
摘要:
The present invention provides for the identification of an antigen surrogate to the native antigens for the autoimmune disease pemphigus vulgaris. Ligands are discovered using large random peptoid or cyclic peptoid libraries that are screened against known antibodies to autoimmune diseases. The ligands may be useful as drugs in the treatment of such diseases and can also be used in combination with the comcomitant removal of T-cells associated with autoimmune disorders.La presente invención se refiere a un método para identificar un ligando peptoide restringido sustituto de antígeno que se reconoce específicamente por autoanticuerpos que comprende: exponer un anticuerpo asociado con una enfermedad autoinmunes seleccionada de pénfigo vulgar a una biblioteca de lingando peptoide que comprende ligandos peptoides de la formula I.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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