Alan B. Cooper,Yongqi Deng,Gerald W. Shipps, Jr.,Neng-Yang Shih,Hugh Y. Zhu,Robert Sun,Joseph M. Kelly,Ronald J. Doll,Yang Nan,Tong Wang,Jagdish A. Desai,James J-S Wang,Youhao Dong,Vincent S. Madison
申请号：
US11810282
公开号：
US08546404B2
申请日:
2007.06.05
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed are the ERK inhibitors of formula 1.0:and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
