A valve stent and a valve prosthesis. The valve stent is in the shape of a mesh tube, and has a compressed state and an expanded state. The valve stent comprises an inflow tract structure (210), a transition tract structure (240), an outflow tract structure (250), and a barb structure. The transition tract structure (240) has a fifth end portion (241), a sixth end portion (242), and a first middle section. In the expanded state, the diameters of the radial sections of the fifth end portion (241) and the sixth end portion (242) are greater than the diameter of the radial section of the first middle section of the transition tract structure (240). The outflow tract structure (250) has a seventh end portion (251) and an eighth end portion (252). The seventh end portion (251) of the outflow tract structure (250) is fixedly connected to the sixth end portion (242) of the transition tract structure (240), and the eighth end portion (252) is a free end. The barb structure is disposed on the transition tract structure (240) and the outflow tract structure (250), and protrudes towards the outside of the transition tract structure (240) and/or the outflow tract structure (250). The valve stent and the valve prosthesis can be stably anchored on natural valves.