CHAMBERS, LAURA J.,GLEAVE, ROBERT,SENGER, STEFAN,WALTER, DARYL SIMON
申请号:
PL07787001
公开号:
PL2049478T3
申请日:
2007.07.03
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
The present invention relates to novel oxo-prolinamide derivatives of formula (I) which modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.