DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION;동국대학교 산학협력단
发明人:
GONG, Young-Dae,공영대,KIM, Soo-Youl,김수열,LEE, Eun Sil,이은실,KOO, Tae-Sung,구태성,KANG, Nam-Sook,강남숙,KIM, Na Yeon,김나연
申请号：
KRKR2017/006004
公开号：
WO2017/213452A1
申请日:
2017.06.09
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention relates to a novel 4-(aryl)-N-(3-alkoxyfuro[3,2-b]pyrazin-2-yl)-piperazine-1-carboxamide derivative compound useful for prevention or treatment of cancer, a method for preparing the same, and a pharmaceutical composition containing the same. A novel 4-(aryl)-N-(3-alkoxyfuro[3,2-b]pyrazin-2-yl)-piperazine-1-carboxamide derivative compound according to the present invention can effectively inhibit proliferative cell growth and thus can be usefully used for prevention or treatment of cancer.La présente invention concerne un nouveau composé dérivé de 4-(aryl)-N-(3-alkoxyfuro[3,2-b]pyrazin-2-yl)-piperazine-1-carboxamide utile dans la prévention ou le traitement du cancer, un procédé de préparation associé, et une composition pharmaceutique le contenant. Un nouveau composé dérivé de 4-(aryl)-N-(3-alkoxyfuro[3,2-b]pyrazin-2-yl)-piperazine-1-carboxamide selon la présente invention peut efficacement inhiber la croissance cellulaire proliférative et peut donc être utile pour la prévention ou le traitement du cancer.본 발명은 암의 예방 또는 치료에 유용하게 사용할 수 있는, 신규한 4-(아릴)-N-(3-알콕시퓨로[3,2-b]피라진-2-일)-피페라진-1-카복스아미드 유도체 화합물, 이의 제조방법 및 이를 포함하는 약학적 조성물에 관한 것이다. 본 발명의 신규한 4-(아릴)-N-(3-알콕시퓨로[3,2-b]피라진-2-일)-피페라진-1-카복스아미드 유도체 화합물은 증식성 세포 성장을 효과적으로 억제할 수 있으므로, 암의 예방 또는 치료에 유용하게 사용될 수 있다.
