胚性幹細胞のインスリン分泌細胞への分化誘導方法、該方法により誘導されるインスリン分泌細胞およびその用途

• 收藏
• 分享

专利权人:

国立大学法人;岡山大学

发明人:

小林 直哉,リヴァス カリーヨ ホルヘデイヴィッド,田中 紀章

申请号：

JP2006326261

公开号：

JP5135577B2

申请日:

2006.12.01

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

A method comprising differentiating embryonic endoderm, which has been differentiated from undifferentiated embryonic stem cells with the use of activin, into neurogenin 3-expressing cells using a conditioned medium, and then stimulating these cells in a glucose-enriched medium to thereby efficiently induce the differentiation thereof into insulin-secreting cells. In addition to the method of inducing the differentiation of embryonic stem cells into insulin-secreting cells, the insulin-secreting cells induced by this method, a remedy for diabetes, a biological artificial pancreas, a research reagent and a model animal for drug design, each containing the above-described cells, are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/