GEIERSTANGER, Bernhard Hubert,SPRAGGON, Glen,BENDER, Steven,CHARLTON, Tracy,GLASER, Scott Martin,KNUTH, Mark,UNO, Tetsuo,KASIBHATLA, Shailaja,GALKIN, Anna,ROTTMANN, Sabine,RUE, Sarah
申请号：
CR20190346
公开号：
CR20190346A
申请日:
2018.02.01
申请国别(地区):
CR
年份:
2019
代理人:
摘要：
This application describes the antibody CR7, its antigen binding fragments, and the drug and antibody complex or antigen binding fragments of these antibodies. The invention also relates to a method for treating or preventing cancer by using antibodies, antigen binding fragments and drugs and antibody conjugates. This document also describes the methods of producing antibodies, antigen binding fragments, drugs and antibody conjugates, as well as the methods of using antigen antibodies and binding fragments as diagnostic reagents.antigen binding fragments thereof and antibody drug conjugates of said antibodies or antigen binding fragments The invention also relates to methods of treating or preventing cancer using the antibodies antigen binding fragments and antibody drug conjugates Also disclosed herein are methods of making the antibodies antigen binding fragments and antibodyEsta solicitud describe anticuerpos anti¿CCR7, sus fragmentos de unión a antígeno y conjugados de fármaco y anticuerpo de dichos anticuerpos o fragmentos de unión a antígeno. La invención también se refiere a métodos para tratar o prevenir el cáncer usando los anticuerpos, los fragmentos de unión a antígeno y los conjugados de fármaco y anticuerpo. En el presente documento también se describen métodos para producir los anticuerpos, los fragmentos de unión a antígeno y los conjugados de fármaco y anticuerpo, y métodos para usar los anticuerpos y los fragmentos de unión a antígeno como reactivos de diagnóstico.This application discloses anti-CCR7 antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating or preventing cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments
