The present invention provides an adhesive preparation, which includes a backing and a pressure-sensitive adhesive layer formed on at least one side of the backing, the pressure-sensitive adhesive layer containing (-)-(R)-N,.alpha.- dimethyl-N-2- propynylphenethylamine and/or a pharmaceutically acceptable salt thereof, a pressure- sensitive adhesive and a component which is liquid at 25°C and has two or more ester bonds in one molecule thereof.