#$%^&*AU2014201546A120141002.pdf#####ABSTRACT This invention provides for an energized biomedical ophthalmic device and associated method of measuring changes in biomarkers contained in tear film to generate data related to a light therapy regimen used to treat symptoms associated with seasonal affective disorder. In some embodiments, the energized biomedical ophthalmic device can include an energized contact lens with a light source in communication with a processor controlling said light source according to the light therapy regimen. The light therapy regimen may be generated or modified by the processor from the measured changes and sometimes from user's preferences, and/or additional measurements, including for example, light exposure and/or circadian rhythm of the user.WEAR ENERGIZED BIOMEDICAL 101 OPHTHALMIC DEVICE ANALYZE TEAR FILM USING ONE OR MORE SENSORS IN/ON THE 105 OPHTHALMIC DEVICE MEASURE LENGTH DETECT CHANGES IN AND/OR INTENSITY OF BIOMARKERS LIGHT RECEIVED BY MONITHMI CORRELATED TO SAD OPHTHALMIC 110 SYMPTOMS 120 ENVIRONMENT 125 (Optional) (Optional) IDENTIFY CHANGE IN ONE OR MORE SAD CORRELATED 115 CONDITION PROVIDE LIGHT THERAPY BASED ON ONE OR MORE OF: CHANGE IN SAD CORRELATED CONDITION, LIGHT EXPOSURE, AND 130 CIRCADIAN RHYTHM Fig. 1 1 of 10