UNIVERSITY OF VIRGINIA PATENT FOUNDATION; D/B/A UNIVERSITY OF VIRGINIA
发明人:
HERR, JOHN C.,PIRES, EUSEBIO S.,HERR, AUSTIN
申请号:
EP13805081
公开号:
EP2861252A4
申请日:
2013.06.13
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides compositions for targeting SAS1B positive cancer cells using immunotoxin technology and discloses that kidney and pancreatic cancer cells are SAS1B positive, but not normal kidney and pancreatic cells. The invention discloses that despite being expressed only in growing oocytes in females among normal tissues SAS1B is expressed in cancers of both men and women.