An intelligent protection device with cleaning and sterilizing function is provided. A protection component of the intelligent protection device is covered and closed to a target. A second pivot of the intelligent protection device is rotated to drive the protection component scrolling and a first pivot of the intelligent protection device rotating. The protection component can be scrolled in the intelligent protection device to clean and sterilize though a spray component to spray cleaning fluid and photocatalyst, a heating component to heat, and an illumination component to illuminate. Therefore, the efficiency of protecting target by the intelligent protection device with cleaning and sterilizing function may be achieved.一種具清潔與殺菌功能的智能保護裝置,於目標物上覆蓋且貼近有保護件,智能保護裝置的第二樞軸轉動以帶動保護件捲動與第一樞軸轉動,使保護件得以捲入智能保護裝置,再透過智能保護裝置中的噴灑元件噴灑清潔液以及光觸媒、加熱元件的加熱以及照射元件的照明,以提供保護件的清潔與殺菌,藉此可以透過智能保護裝置的清潔與殺菌功能達到保護目標物的技術功效。10‧‧‧第一組件11‧‧‧第一底座12‧‧‧第一蓋體121‧‧‧第一開槽13‧‧‧第一樞軸20‧‧‧第二組件21‧‧‧第二底座22‧‧‧第二蓋體221‧‧‧第二開槽23‧‧‧第二樞軸24‧‧‧噴灑元件241‧‧‧清潔液儲存槽2411‧‧‧第一感測器偵測242‧‧‧光觸媒儲存槽2421‧‧‧第二感測器偵測25‧‧‧加熱元件251‧‧‧加熱源26‧‧‧照射元件261‧‧‧紫外光光源27‧‧‧控制元件