This invention relates to tritoqualine for use in the treatment of cystic fibrosis or any other fibrosis disease associated with IL-8. The invention also relates to the method for the treatment of cystic fibrosis or any other fibrosis disease associated with IL-8 by administering tritoqualine. The invention can be used to improve the condition of individuals with any fibrosis disease associated with IL-8, and in particular cystic fibrosis.