David J. Chaplin,Klaus Edvardsen,Kevin G. Pinney,Joseph Anthony Prezioso,Mark Wood
申请号:
US10790662
公开号:
US08198302B2
申请日:
2004.03.01
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Novel quinone and catechol compositions, compositions containing prodrugs of quinone and catechol compositions, and methods of use for the treatment of solid tumor cancers and other vascular proliferative disorders. The disclosure particularly relates to the discovery of dual activity agents capable of generating both a vascular targeting effect and direct tumor cell cytotoxicity in order to achieve an enhanced anti-tumor response in a patient.