Methods and apparatus provide evaluation of a cardiac condition of a patient with sleep disordered breathing. One or more processors, such as processors associated with any of ICDs, CRTs and/or respiratory pressure therapy devices, may be configured to receive data representing one or more respiratory parameters for the patient. The processor(s) may receive cardiac-related patient data for the patient. The processor(s) may determine a presence of a smooth hemodynamic baseline from the received data representing one or more respiratory parameters for the patient. The processors may evaluate the cardiac condition of the patient from the received cardiac-related patient data based on the determined presence of the smooth hemodynamic baseline.