Joseph Burlison;Dinesh U. Chimmanamada;Minghu Song;Junghyun Chae;Weiwen Ying;Shijie Zhang
发明人:
Weiwen Ying,Dinesh U. Chimmanamada,Joseph Burlison,Shijie Zhang,Minghu Song,Junghyun Chae
申请号:
US13057962
公开号:
US09126953B2
申请日:
2009.08.07
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to substituted pyrrole compounds of formula I and compositions comprising substituted tri-substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a tri-substituted’ triazole compound of the invention, or a pharmaceutical composition comprising such a compound.