ULLOA, SERGIO R.,VILLACAMPA RAMOS, JOSE DE JESUS MATEO,JUAREZ VARGAS, LUIS JAVIER
申请号：
CA2653955
公开号：
CA2653955C
申请日:
2007.06.01
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The invention discloses a pharmaceutical composition comprising phenylephrine in a sustained-release formulation alone or in combination with another active such as an antihistamine, an analgesic, an antipyretic or a non-steroidal anti-inflammatory agent or a mixture of two or more other actives. In a preferred embodiment, the composition comprises a solid dosage form with hydroxypropyl methylcellulose and carboxymethyl cellulose sodium as a matrix for sustained release of phenylephrine. Phenylephrine is released over a prolonged period of time by the solid dosage form essentially independent of pH.
