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APPLICATION OF THE COMBINATION OF UDENAFIL AND ALFUZOSIN OR OXIBUTININ FOR THE TREATMENT OF A HYPERACTIVE URINARY BLADDER
专利权人:
ПЕЛВИФАРМ (FR)
发明人:
ЖУЛИАНО Франсуа (FR),БЕР-РУССЕЛЬ Дельфин (FR)
申请号:
RU2010144795/15
公开号:
RU2010144795A
申请日:
2009.04.02
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A pharmaceutical composition containing two active substances, udenafil and either alfuzosin, or an antimuscarinic agent selected from the group of oxybutynin, tolterodine, darifenacin, solifenacin and trospium, or a pharmaceutically acceptable salt, solvate, prodrug or hydrate of any of these substances. ! 2. The pharmaceutical composition according to claim 1, in which the antimuscarinic agent is oxybutynin or a pharmaceutically acceptable salt, solvate, prodrug or hydrate thereof. ! 3. The pharmaceutical composition according to claim 1, made in the form of a standard dosage form. ! 4. The pharmaceutical composition according to claim 1, in which each active substance is contained in a separate dosage form. ! 5. The pharmaceutical composition according to claim 1, in which the formulation of the two active substances is developed in the form of a solid dosage form. ! 6. A method of treating an overactive bladder, benign prostatic hyperplasia and lower urinary tract symptoms, comprising administering to a patient in need of a therapeutically effective amount of a composition containing two active substances: udenafil and either alfuzosin, or an antimuscarinic agent selected from the group of oxybutynin, tolteradine, darifenacin , solifenacin, and trospium, or a pharmaceutically acceptable salt, solvate, prodrug, or hydrate of any of these substances. ! 7. The method according to claim 6, in which the formulation of the two active substances is developed in the form of a standard dosage form. ! 8. The method according to claim 6, in which the formulation of each active substance is developed in the form of separate dosage forms. ! 9. The method according to claim 6, in which two active substances1. Фармацевтическая композиция, содержащая два активных вещества, уденафил и либо алфузозин, либо антимускариновое средство, выбранное из группы оксибутинина, толтеродина, дарифенацина, солифенацина и троспиума, или фармацевтически приемлемую соль, сольват, пролекарство
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