A method of assisting a caregiver in delivering patient therapy includes providing prompts at a user interface, wherein the therapy includes steps in a protocol, at least one of which is an instruction for the caregiver to call the ERC by actuating the input device, initiating a call to an emergency response center (ERC) in response to actuation of an input device of a medical device, detecting, by one or more sensors, whether one or more steps of the protocol have been completed in response to the prompts, wherein at least one of the sensors is a sensor other than a therapy electrode, selecting one or more prompts based at least in part on whether the one or more steps in the series has been performed, and controlling the user interface to provide the selected one or more prompts as visible and/or audible prompts.