KAMAEV, Pavel,FRIEDMAN, Marc,SHERR, Evan,PETERSON, Sarah, M.,MULLER, David
申请号：
EP15864372
公开号：
EP3226871A4
申请日:
2015.12.02
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Systems, methods, and compositions generate cross-linking activity for treatment of eye disorders. Various agents, additives, buffers, etc., may be employed in formulations with a cross-linking agent to enhance treatment. For example, a composition for applying treatment to a cornea of an eye includes a cross-linking agent that generates cross-linking activity in the cornea in response to exposure to a photo-activating light. The composition also includes an iron additive and citrate buffer. In some cases, the cross-linking agent may include riboflavin. In other cases, the iron additive may include FeSO4. In further cases, the iron additive may be dissolved in the citrate buffer.
