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Novel therapeutic uses of benzylideneguanidine derivatives for the treatment of proteopathies
专利权人:
Inflectis Bioscience
发明人:
Guedat, Philippe
申请号:
AU2015282900
公开号:
AU2015282900A1
申请日:
2015.07.02
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention relates to novel uses of a compound of formula (I), or a tautomer and/or a pharmaceutically acceptable salt thereof, in treating a disorder associated with the PPP1R15A pathway and associated with protein misfolding stress and in particular with accumulation of misfolded proteins selected in the group of tauopathies, synucleinopathies, polyglutamine and polyalanine diseases, leukodystrophies, cystic fibrosis, multiple sclerosis, lysosomal storage disorders, amyloidosis diseases, inflammation, metabolic disorders, cardio-vascular disorders, osteoporosis, nervous system trauma, ischemia.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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