THE GENERAL HOSPITAL CORPORATION;TRUSTEES OF BOSTON UNIVERSITY
发明人:
Firas M. EL-KHATIB,Edward R. DAMIANO,Steven J. RUSSELL
申请号：
US15748333
公开号：
US20180220942A1
申请日:
2016.08.08
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A glucose control system employs adaptation of a glucose target (set-point) control variable in controlling delivery of insulin to a subject to maintain euglycemia. The glucose target adapts based on trends in actual glucose level (e.g., measured blood glucose in the subject), and/or computed doses of a counter-regulatory agent such as glucagon. An adaptation region with upper and lower bounds for the glucose target may be imposed. Generally the disclosed techniques can provide for robust and safe glucose level control. Adaptation may be based on computed doses of a counter-regulatory agent whether or not such agent is actually delivered to the subject, and may be used for example to adjust operation in a bihormonal system during periods in which the counter-regulatory agent is not available for delivery.
