6-cycloalkyl-1,5-dihydro-pyrazolo [3,4-d] pyrimidin-4-one derivatives and their use as pde9a inhibitors

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

EICKMEIER CHRISTIAN,SCHAENZLE GERHARD,HEINE NIKLAS,FERRARA MARCO,ROSENBROCK HOLGER,GIOVANNINI RICCARDO

申请号：

NZ60372511

公开号：

NZ603725A

申请日:

2011.08.09

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

The disclosure relates to a class of 6-cycloalkyl-pyrazolopyrimidinone (a ketone of a pyrazolopyrimidine structure) compounds according to the drawing, wherein R1 and D are defined in the specification. The compounds of the invention show PDE9 inhibiting properties. These compounds can then be used as the active entity of medicaments, or for the manufacture of medicaments, for the treatment of conditions concerning deficits in perception, concentration, learning or memory, including Alzheimers disease and schizophrenia.

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