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Anti-Folate Receptor Alpha Antibodies And Uses Thereof
专利权人:
发明人:
Daniel John OShannessy,Elizabeth B. Somers
申请号:
US15821296
公开号:
US20180148504A1
申请日:
2017.11.22
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein are antibodies, and antigen-binding fragments thereof, that are specific for folate receptor alpha, related polynucleotides, expression vectors, and cells that express the described antibodies. Also provided are methods of using the described antibodies, and antigen-binding fragments thereof, and related kits to detect folate receptor alpha. Provided herein are also methods for diagnosing folate receptor alpha-expressing cancers using the described antibodies, and antigen-binding fragments thereof. The methods involve determining the amount of folate receptor alpha in a sample derived from a subject and comparing this level with the level of folate receptor alpha in a control sample or reference sample.
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