PCSK9抗體、其抗原結合片段及其醫藥用途

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专利权人:

JIANGSU HENGRUI MEDICINE CO., LTD.;SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.;SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.;上海恒瑞醫藥有限公司

发明人:

QU, Xiangdong,YE, Xin,XU, Shaoyu,YUAN, Bei,CUI, Dongbing,HU, Qiyue,ZHANG, Lei,XU, Zhibin,TAO, Weikang,ZHANG, Lianshan,SUN, Piaoyang,胡齊悦,ZHANG, Lei,張蕾,XU, Zhibin,許志賓,TAO, Weikang,陶維康,ZHANG, Lianshan,張連

申请号：

HK18104378.4

公开号：

HK1244828A

申请日:

2018.04.02

申请国别(地区):

HK

年份:

2018

代理人:

摘要：

The present invention provides a PCSK9 antibody, an antigen-binding fragment thereof, and a medicinal application thereof. Provided in the invention is a chimeric antibody and a humanized antibody, both comprising a CDR of the PCSK9 antibody, and a pharmaceutical composition comprising the PCSK9 antibody and an antigen-binding fragment thereof, and an application of the PCSK9 antibody as a lipid-lowering agent. The invention specifically relates to an application of a humanized PCSK9 antibody for preparing a pharmaceutical drug to treat a PCSK9-induced disease or symptom.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/