Karl Kolter,Silke Gebert,Sandra Kruse,Michael Schönherr
申请号:
US13416558
公开号:
US20120231042A1
申请日:
2012.03.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Provided are pharmaceutical formulations in the form of granules comprisinga) about 60-96% by weight of non-film-forming sugars or sugar alcohols,b) about 1-10% by weight of film-forming sugars or sugar alcohols,c) about 3-25% by weight of disintegrants,d) about 0-10% by weight of water-insoluble, film-forming polymerse) about 0-15% by weight of further pharmaceutically customary auxiliaries where the sum of components a) to e) is 100% by weight. Also provided are methods of making and using the pharmaceutical formulations described herein.