A safety protection device for injection syringe includes a locking ring and a protective sleeve. The protective sleeve can be positioned on the injection syringe or move forward to cover the needle body of the injection syringe through the locking ring fixed on the injection syringe, and the protective sleeve covering the needle body cannot be returned due to the limitation of the locking ring.一種注射針筒安全保護裝置,該保護裝置包括一鎖定環和一保護套,該保護套透過固定在注射筒上的該鎖定環而可定位在注射筒上或者往前移動遮蔽該注射筒的針體,且遮蔽該針體之保護套因該鎖定環之限制而無法再退回。