Compositions of buprenorphine and mu-opioid receptor antagonists

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专利权人:

ALKERMES PHARMA IRELAND LIMITED

发明人:

DEAVER DANIEL,EHRICH ELLIOT

申请号：

NZ62405612

公开号：

NZ624056A

申请日:

2012.12.14

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

The disclosure relates to a composition comprising buprenorphine and a &mu opioid receptor antagonist, wherein the composition is characterized by an Agonist Antagonist Activity Index (AAnAI) of between about 0.75 and about 2.2. The composition may comprise an antagonist of formula I. The composition may be used to treat a depressive disorder.

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