There is provided a modular medication dispensing system for managing and automatically dispensing pills from a plurality of portable medication dispensers, the modular system comprising: a base equipped with rotation means and being removably installed on a plane surface, a circular magazine comprising a plurality of adaptors for receiving a plurality of portable medication dispensers, the circular magazine being rotatably mounted on the base, an actuator for actuating a portable dispenser from the plurality of portable dispensers when the portable dispenser is in the dispensing position, a plurality of autonomous portable dispensers being removably received in the plurality of adaptors and operating autonomously or in synchronization with the modular system, a filling assembly comprising movable means for automatically filling a portable dispenser, and an electronic system comprised in each portable dispenser and in the base for permanently communicating between the plurality of portable dispensers and the base or between the base and a doctor, a pharmacist or one's smart phone or between the portable dispensers and a doctor, a pharmacist or one's smart phone using network protocols and for automatically dispensing medication once dispensing periods are reached.