COMPOSITIONS COMPRENANT UN INHIBITEUR DES PROPRIETES DE TYPE CELLULES SOUCHES DE CANCERS ET UN AGENT IMMUNOTHERAPEUTIQUE POUR UNE UTILISATION DANS LE TRAITEMENT DU CANCER
LI, CHIANG J.,LI, YOUZHI,GAO, YUAN,WANG, YUXIN,HUANG, JANET,ROGOFF, HARRY
申请号:
CA2988126
公开号:
CA2988126A1
申请日:
2016.06.03
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Disclosed herein are methods for use in treating cancer comprising administering at least one cancer sternness inhibitor, for example, at least one STAT3 pathway inhibitor such as 2-acetylnaphtho [2, 3 -b] furan-4, 9-dione, in order to sensitize or re-sensitive a cancer that is naive, resistant, or/and refractory to at least one immunotherapeutic agent, such as at least one immune checkpoint modulator.