VICAL INCORPORATED;WISCONSIN ALUMNI RESEARCH FOUNDATION
发明人:
申请号：
EP00108872.3
公开号：
EP1026253B2
申请日:
1990.03.21
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate, comprising the interstitial introduction of an isolated polynucleotide into a tissue of the vertebrate where the polynucleotide is taken up by the cells of the tissue and exerts a therapeutic effect on the vertebrate. The method can be used to deliver a therapeutic polypeptide to the cells of the vertebrate, to provide an immune response upon in vivo translation of the polynucleotide, to deliver antisense polynucleotides, to deliver receptors to the cells of the vertebrate, or to provide transitory gene therapy.
