Optical imaging systems and methods are disclosed herein for investigating and analyzing one or more characteristics of a spray, including spray front velocity, spray sheet length, spray break-up dynamics, drift potential, and drop-size distribution. Optical imaging systems disclosed herein include an image acquisition device, one or more illumination source, a processor for processing and analyzing image data, a background, and a spray system that includes at least a nozzle. The image acquisition device and illumination sources are positioned on the same side of the spray. The processor has a first algorithm to generate a feedback correction factor and a second algorithm to identify droplets and develop a drop-size distribution for the spray. Optical imaging methods for determining spray characteristics are also disclosed and generally include the steps of providing an imaging system, capturing images of the spray with the imaging system, processing the images, and analyzing the images.