PROBLEM TO BE SOLVED: To provide an oral composition effective in alleviating the symptoms of the "I type allergy" caused by releasing physiologically active substances (degranulation) such as histamine from mast cells or basophilic cells, including allergy particularly atopic dermatitis, asthma, hives, and hay fever.SOLUTION: β-lactoglobulin or β-lactoglobulin and nobiletin are used as an active ingredient.SELECTED DRAWING: None