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Phenylpyrimidone compounds, the pharmaceutical compositions, preparation methods and uses thereof
专利权人:
Jingkang Shen;Guanghui Tian;Yi Zhu;Jingshan Shen;Xiaojun Yang;Jinfeng Zhang;Qing Jin;Zheng Liu;Zhen Wang;Weiliang Zhu;Hualiang Jiang;Jianfeng Li
发明人:
Zheng Liu,Jianfeng Li,Xiaojun Yang,Zhen Wang,Jinfeng Zhang,Yi Zhu,Guanghui Tian,Qing Jin,Jingkang Shen,Weiliang Zhu,Hualiang Jiang,Jingshan Shen
申请号:
US13139156
公开号:
US08871777B2
申请日:
2009.12.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds of the following formula I, the pharmaceutically acceptable salts or solvates thereof and to the pharmaceutical composition as well as the preparation method of the compounds. The compounds of formula I according to the present invention can effectively inhibit type V phosphodiesterase (PDE5), and thus can be used for the treatment of various vascular disorders, such as male erectile dysfunction, pulmonary hypertension and the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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