Erning Xia,Susan E. Burke,Srini Venkatesh,Vicki L. Barniak
申请号：
US13553919
公开号：
US20120283333A1
申请日:
2012.07.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Ophthalmic compositions that comprise 0.5 ppm to 15 ppm α-[4-tris(2-hydroxyethyl)-ammonium chloride-2-butenyl]poly[1-dimethyl ammonium chloride-2-butenyl]-Ω-tris(2-hydroxyethyl) ammonium chloride 0.005 wt. % to 0.05 wt. % hyaluronic acid citrate, citric acid or a mixture thereof and 0.01 wt. % to 0.8 wt. % of an amphoteric surfactant of general formula Iwherein R1 is R or —(CH2)n-NHC(O)R, wherein R is a C8-C30alkyl optionally substituted with hydroxyl and n is 2, 3 or 4 R2 and R3 are each independently selected from the group consisting of hydrogen and C1-C4alkyl R4 is a C2-C8alkylene optionally substituted with hydroxyl and Y is CO2− or SO3−. The invention is also direct to the use of the ophthalmic compositions to clean and disinfect contact lenses, and in particular, soft, silicone hydrogel contact lenses.
