UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
发明人:
MA, JIANJIE,WEISLEDER, NOAH,CAI, CHUANXI
申请号:
CA2657319
公开号:
CA2657319C
申请日:
2007.07.11
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Disclosed herein are nucleic acid sequences that encode novel MG53polypeptides.Also disclosed are polypeptides encoded by these nucleic acid sequences, andantibodies, which immunospecifically-bind to the polypeptide, as well asderivatives,variants, mutants, or fragments of the aforementioned polypeptide,polynucleotide, orantibody. The invention further discloses the use of these MG53 polypeptidesintreatment and prevention of cellular damage as well as therapeutic, diagnosticandresearch methods for diagnosis, treatment, and prevention of disordersinvolving anyone of these novel human nucleic acids and proteins.