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AUGMENTATION DU RENDEMENT EN PARTICULES DE TYPE VIRAL DANS DES PLANTES
专利权人:
MEDICAGO INC.
发明人:
D'AOUST, MARC-ANDRE,COUTURE, MANON,VEZINA, LOUIS-PHILIPPE
申请号:
CA2850407
公开号:
CA2850407A1
申请日:
2012.09.28
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
A method of producing a virus like particle (VLP) in a plant is provided. The method comprises introducing a first nucleic acid and a second nucleic acid into the plant, or portion of the plant. The first nucleic acid comprises a first regulatory region active in the plant and operatively linked to a nucleotide sequence encoding a structural virus protein. The second nucleic acid comprises a second regulatory region active in the plant and operatively linked to a nucleotide sequence encoding a channel protein, for example but not limited to a proton channel protein. The plant or portion of the plant is incubated under conditions that permit the expression of the nucleic acids, thereby producing the VLP.
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