COMPOSITION PHARMACEUTIQUE DESTINÉE À PRÉVENIR OU À TRAITER DES MALADIES ASSOCIÉES À DYRK, COMPRENANT UN COMPOSÉ À BASE DE PYRIDINE COMME PRINCIPE ACTIF
Korea Research Institute of Bioscience and Biotechnology;Korea Research Institute of Chemical Technology
发明人:
CHO, Sungchan,CHOI, Miri,LEE, Joo Youn
申请号:
EP17881667
公开号:
EP3542797A4
申请日:
2017.12.15
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention relates to a pharmaceutical composition the prevention or treatment of DYRK-related diseases containing a pyridine-based compound as an active ingredient, a pyridine-based compound of the present invention which is used as an active ingredient of the pharmaceutical composition inhibits the activity of DYRK1A with very high efficacy and selectivity, thereby can be used effectively in the prevention or treatment of DYRK-related diseases, such as Down syndrome, degenerative brain diseases, cancer, and metabolic diseases.