The present invention is provided to pharmaceutical composition is administered to the composition and method of human patients. The composition is administered orally once a day with treatment effective dose to patient. Described pharmaceutical composition include selected from by Brivaracetam, double valproates, lacosamide, Levetiracetam, Oxcarbazepine, sabril and it is aforementioned in drug and at least one excipient in the group that forms of any one pharmaceutically acceptable salt. At least one of described at least one excipient changes the release of the drug to provide extended release mode. Described pharmaceutical composition has pharmacokinetic properties described in claim.