Institut National De La Recherche Agronomique;The Royal Institution For The Advancement Of Learning/McGill University
发明人:
Anne LESPINE,Roger PRICHARD,Cecile MENEZ
申请号：
US15988073
公开号：
US20180265536A1
申请日:
2018.05.24
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to the use of avermectin derivative as a drug for the treatment of parasitic infections. The avermectin derivative is represented by the formula (I) wherein: (i) R1 is chosen from the group constituted of —CH(CH3)2, —CH(CH3)CH2CH3, or cyclohexyl, (ii) X represents —CH2—CH2—, or —CH═CH—, (iii) R2 is chosen fromor an OH group, (iv) R3 is OH or NOH, (v) represents a single bond when R3 is OH, or a double bond when R3 is NOH, as an inhibitor of a membrane-bound protein which transports exogenous compounds out of target cells.
