A needle retraction apparatus for a medical device such as a liquid infusion or collection device, the apparatus having a body, a needle retraction mechanism seated inside the body, a transverse slide member with an external needle retraction chamber, and a retraction actuator that is rotatable relative to the slide member, the retraction actuator being attachable to or made as part of the liquid infusion or collection device, whereby rotation of the device causes the slide member to move in a linear translational direction to reposition the retraction chamber in alignment with the needle retraction mechanism and allow retraction.