Provided are: an excellent anti-human NGF antibody fragment that maintains high neutralizing activity and exhibits localized action while reducing systemic side effects from systemic exposure； and a therapeutic procedure for postoperative pain using the antibody fragment. An anti-human NGF antibody Fab fragment which includes a heavy chain fragment comprising the amino acid sequence indicated in SEQ ID NO:5 and a light chain comprising the amino acid sequence indicated in SEQ ID NO:8.本發明提供一種可保持較高的中和活性，可展現在局部之藥效，而且可降低因全身暴露所引起之全身性的副作用的優良之抗人類NGF抗體片段、及、使用該抗體片段之術後疼痛之治療手段。一種抗人類NGF抗體Fab片段，其係包含由序列編號5所示之胺基酸序列構成的重鏈片段及由序列編號8所示之胺基酸序列構成的輕鏈。
